Fluticasone Propionate

Allergic cascade

Interrupts key moments in the early- and late- phases of the allergic cascade2

FLONASE® blocks 6 of the key inflammatory mediators, including histamine, cytokines, leukotrienes, chemokines, prostaglandins, and tryptase.2

In addition, FLONASE® binds to the glucocorticoid receptor to control gene expression inside the cell–either by binding as a complex to response elements in promoter regions of responsive genes or directly inhibiting gene transcription factors. The latter action leads to the downregulation of the production of cytokines and other inflammatory molecules.2

AR can strike at any time & have a significant negative impact on your patients’ quality of life.3


FLONASE® Allergy Relief

Help your patients when they need it most to get relief with FLONASE® Allergy Relief.

FLONASE ® Allergy Relief blocks 6 key inflammatory mediators for effective relief from nasal and ocular symptoms. 2,4,5

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