Overview

Advil mechanism of action video

Advil contains ibuprofen — a nonsteroidal anti-inflammatory drug (NSAID).

The principal mechanism of action of ibuprofen and other NSAIDs is decreasing prostaglandin biosynthesis, by inhibiting cyclooxygenase.1

Prostaglandins are naturally occurring fatty acid derivatives that are widely distributed in the tissues. They are believed to be a common factor in the production of pain, fever, and inflammation.1

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Advil used by millions of people

Demonstrated efficacy and a well-established safety profile1,2,5*

One Advil is often all it takes to relieve mild to moderate acute pain including:1

  • Sore throat pain
  • Headache & migraine
  • Muscle aches
  • Menstrual pain
  • Toothache (dental pain)

Advil also reduces fever.

There is considerable evidence documenting the efficacy of both the 200 mg and 400 mg doses of ibuprofen in the treatment of mild to moderate acute pain in a range of pain models.1

Low dose (<1200 mg/day) and short duration use of ibuprofen has a well-demonstrated clinical tolerability profile comparable to acetaminophen.1,6-9

* Advil should not be taken for fever for more than 3 days or for pain for more than 5 days unless directed by a physician. Please consult the Product Monograph for complete dosing and safety profile.1Please consult the Product Monograph available upon request (1-855-367-7349) or on the Health Canada website₹for information to assist in benefit-risk assessment. Always direct the patient to read the label.

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Advil manages acute pain and fever with a range of well-studied and effective pain-relieving products.

Ibuprofen containing products

Liqui-Gels Ibuprofen Capsules, 200 mg

Advil Liqui-Gels Ibuprofen Capsules, 200 mg

Relieves migraines, headaches, fever, muscle & joint pain.1

12 Hour Ibuprofen Extended Release Tablets BP, 600 mg

Advil 12 Hour Ibuprofen Extended Release Tablets BP, 600 mg

Designed with dual-layer technology for up to 12 hours of pain relief with one pill.1

Children’s Advil Pediatric Drops

Children’s Advil Pediatric Drops Ibuprofen Oral Suspension, 40 mg/mL

Relieves fever for up to 8 hours. Includes an oral syringe for precise dosing. For ages 4 months to 3 years.2

Children’s Advil Suspension

Children’s Advil Ibuprofen Oral Suspension, 100 mg/5 mL

Reduces fever and relieves pain, providing up to 8 hours of relief.2

Children’s Advil Chewable Tablets

Children’s Advil Chewable Ibuprofen Tablets, 100 mg

Relieves fever and pain due to colds or flu, sore throat, immunization, and earache. Ages 2–12 years.2

Advil — for all your patients’ acute pain relief needs

Conditions

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Advil products

Advil products

Help your patients manage their acute pain and fever with our full range of well studied and effective pain-relieving products.1,2,5

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