Pronamel Science
The specially formulated formulation of Pronamel1–10
The special formulation of Pronamel delivers minerals into the enamel to help strengthen and protect teeth7,11
A special formulation that delivers strong fluoride uptake*1,2
Pronamel contains 1150ppm fluoride in a special formulation designed to maximise intra-oral fluoride. By omitting components that inhibit fluoride uptake, which are present in many other fluoride toothpastes, this Pronamel formulation enhances remineralisation and inhibits demineralisation, strengthening and protecting enamel.1–4
Pronamel special formulation:
- No phosphates2,6,7
- No polyvalent metal ions7
- Ionic form of fluoride7
- No SLS8
- Neutral pH9
- Low abrasivity†10,12
SLS, sodium lauryl sulphate*Compared with tested, standard formulated fluoride toothpastes†Only Pronamel Daily Protection, Pronamel Extra Freshness and Pronamel For Children
How enamel is affected by enamel erosion
Enamel undergoes natural dynamic cycles of remineralisation and demineralisation,22-23 normally favouring remineralisation due to mineral-rich saliva, which helps neutralize acidity and reharden enamel.
However, exposure to gastric or dietary acids can demineralize and weaken enamel, causing it to lose some of its mineral content. If the acid attack happens frequently, the enamel does not have a chance to repair itself.26,27
Not all fluoride toothpastes are the same5,15
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Pronamel maintains higher levels of fluoride
In an in situ study against a standard fluoride toothpaste, the Pronamel formulation maintained higher levels of fluoride in subjects’ saliva 1 hour after brushing.3
Adapted from GSK data on file RH02217, 20143
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Pronamel creates an environment in the mouth that supports remineralisation3
In an in situ study against a standard fluoride toothpaste, the special Pronamel formulation1 maintained higher calcium bioavailability in subjects’ saliva.
Adapted from GSK data on file RH02217, 20143
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Delivers fluoride deep into the enamel for better remineralization24
Pronamel delivers fluoride deep into the enamel for better remineralization24
In this In vitro study, Pronamel delivered more fluoride into the enamel for better remineralisation vs. a standard fluoride toothpaste.*24
In vitro cross-sectional DSIMS images of enamel surfaces
DSIMS, dynamic secondary ion mass spectrometry
*Based on mean fluoride/oxygen ratio measured at a depth of 10μm; vs. a non-specially formulated fluoride toothpaste
†Sourced and tested in 2016 -
Pronamel improves mineral uptake, leaving enamel more resilient to subsequent acid challenge8
In this in situ study, Pronamel provided an increase in surface microhardness of acid-softened enamel7
Adapted from Barlow et al. 20097 Colgate Sensitive Multi Protection Sourced and Tested in 2008.
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A gentle formulation helps ensure minimal wear of acid-weakened enamel10
Pronamel has a low abrasion formula, helping to maintain the structural integrity of the enamel surface.*10
In vitro SEM cross-sectional images of enamel surface structure*Pronamel Daily Protection and Pronamel Extra Fresh only
Pronamel Toothpaste
Pronamel products are designed to help protect against enamel wear due to acids7,17,19–21
Pronamel – helping protect your patients against enamel wear due to acids
The Pronamel range
Pronamel strengthens and protects tooth enamel. See which formula in our product line is right for your patients.
