FLONASE Product Overview

FLONASE allergy relief—the efficacy of prescription fluticasone propionate, with OTC benefits¹

For patients who were well-controlled on a prescription INCS and need OTC convenience, FLONASE Allergy Relief offers the allergy relief it had as a prescription with the benefits of a branded OTC medicine.¹

Same prescription strength, 24-hour relief¹

The #1-prescribed INS ingredient* for allergic rhinitis is available OTC—delivers the same trusted, prescription-strength relief.^2-14
Relieves the symptoms of seasonal and perennial allergic rhinitis¹

In addition to treating congestion, runny nose, sneezing, and itchy nose, FLONASE Allergy Relief is the first OTC INS indicated to relieve itchy, watery eyes.^2-13
Recommended first-line, long-term¹⁵

INSs such as FLONASE Allergy Relief are recommended for initial and maintenance treatment of nasal allergies.^† 3,15

First-line nasal allergy treatment: Allergic Rhinitis and its Impact on Asthma (ARIA) treatment guidelines, issued in partnership with the World Health Organization, recommend INS treatments like FLONASE as first-line treatment for allergic rhinitis, calling them “the most effective drugs”.^3,15,16

Long-term nasal allergy treatment: INS treatments are recognized as the most effective, long-term treatment option for allergic rhinitis^†3,15,16

Prescription-Strength Fluticasone Propionate, Available OTC¹

Flonase allergy relief product overview 1

Flonase allergy relief product overview 2

FLONASE—Gold-standard INS efficacy for more complete 24-hour allergy relief^‡1,2,15-21

Read more about Flonase products

FLONASE SENSIMIST Allergy Relief

Find out how FLONASE SENSIMIST Allergy Relief can help your patients.

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Children’s FLONASE SENSIMIST Allergy Relief

Find out how Children’s FLONASE SENSIMIST Allergy Relief can help your patients.

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Children’s FLONASE Allergy Relief

Find out how Children’s FLONASE Allergy Relief can help your patients.

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Allergic Rhinitis Overview

Find out more about allergic rhinitis

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Causes and Mechanisms

Find out more about the science of allergic rhinitis

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Patient care resources

Download resources for your patients.

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Patient FSA / HSA Eligible Product

This product is eligible for Flexible Spending Account (FSA) and Health Savings Accounts (HSA)

Resulting from the CARES Act recently passed by congress, you can now use your FSA and HSA tax-preferred savings account to purchase certain OTC products such as Flonase, Nicorette, Nicoderm, Advil, Voltaren, and Denture Care Products. Your plan details may vary, so make sure to save your receipt and check with your benefits or health provider for eligibility. Please visit our page on Using My FSA/HSA.

*Based on IMS Health NPA Audit MAT (October 2010-September 2016).
†The Joint Task Force on Practice Parameters (the American Academy of Allergy Asthma & Immunology; the American College of Allergy, Asthma, and Immunology; and the Joint Council of Allergy, Asthma and Immunology).
**Mechanism vs most OTC allergy pills. FLONASE acts on multiple inflammatory substances (histamine, prostaglandins, cytokines, tryptases, chemokines, and leukotrienes). The exact number and precise mechanism are unknown.^17-20
††Data vs. loratadine
‡Vs. single-ingredient antihistamines which do not treat nasal congestion.

References

FLONASE Drug Facts Label.
Greiner AN, Meltzer EO. Overview of the Treatment of Allergic Rhinitis and Nonallergic Rhinopathy. Proc Am Thorac Soc 2011;8:121-131.
Wallace DV, Dykewicz MS. The diagnosis and management of rhinitis: An updated practice parameter. J Allergy Clin Immunol. 2008;122(2):S1-S84.
Nathan RA, Bronsky EA, Fireman P, et al. Once daily fluticasone propionate aqueous nasal spray is an effective treatment for seasonal allergic rhinitis. Ann Allergy 1991;67:332-338.
Banov CH, Woehler TR, LaForce CF, et al. Once daily intranasal fluticasone propionate is effective for perennial allergic rhinitis. Ann Allergy 1994;3:240-246.
Dykewicz MS, Kaiser HB, Nathan RA, et al. Fluticasone propionate aqueous nasal spray improves nasal symptoms of seasonal allergic rhinitis when used as needed (prn). Ann Allergy Asthma Immunol 2003;91:44-48.
Scadding GK, Lund VJ, Jacques LA, Richards DH. A placebo-controlled study of fluticasone propionate aqueous nasal spray and beclomethasone dipropionate in perennial rhinitis: efficacy in allergic and non-allergic perennial rhinitis. Clin Exp Allergy 1995;25:737-743.
van As A, Bronsky EA, Dockhorn RJ, et al. Once daily fluticasone propionate is as effective for perennial allergic rhinitis as twice daily beclomethasone diproprionate. J Allergy Clin Imunol 1993;91(6):1146-1154.
Data on file, GlaxoSmithKline. GSK: Result Summary for Study FNM40184. http://www.gsk-clinicalstudyregister.com/. 12-19-2005.
Haye R, Gomez EG. A multicentre study to assess long-term use of fluticasone propionate aqueous nasal spray in comparison with beclomethasone dipropionate aqueous nasal spray in the treatment of perennial rhinitis. Rhinology 1993;31:169-174.
Bernstein DI, Levy AL, Hampel FC, et al. Treatment with intranasal fluticasone propionate significantly improves ocular symptoms in patients with seasonal allergic rhinitis. Clin and Exp Allergy 2004;34(6):952-957.
DeWester J, Philpot EE, Westlund RE, Cook CK, Rickard KA. The Efficacy of Intranasal Fluticasone Propionate In the Relief of Ocular Symptoms Associated with Seasonal Allergic Rhinitis. Allergy Asthma Proc 2003;24(5):331-337.
Data on file, GlaxoSmithKline. GSK: Result Summary for Study FNM30034. http://www.gsk-clinicalstudyregister.com/. 5-12-2005.
IMS Health Incorporated. IMS National Prescription Audit MAT (DATES TO COME)
Bousquet J, Khaltaev N, Cruz AA, et al. Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 - in collaboration with the World Health Organization, GA²LEN and AllerGen. Allergy 2008;63(Suppl. 86):8-160.
Derendorf H, Meltzer EO. Molecular and clinical pharmacology of intranasal corticosteroids: clinical and therapeutic implications. Allergy 2008;63:1292-1300.
Gelfand EW. Inflammatory mediators in allergic rhinitis. J Allergy Clin Immunol 2004;114(5):135-138.
White MV, Kaliner MA. Mediators of allergic rhinitis. J Allergy Clin Immunol 1992;90(4):699-704.
Bachert C, Geveart P. Effect of intranasal corticosteroids on release of cytokines and inflammatory mediators. Allergy 1999;54(57):116-123.
van As A, Bronsky E, Grossman J, Meltzer E, Ratner P, Reed C. Dose tolerance study of fluticasone propionate aqueous nasal spray in patients with seasonal allergic rhinitis. Ann Allergy 1991;67:156-162.
Benincasa C, Lloyd RS. Evaluation of Fluticasone Propionate Aqueous Nasal Spray Taken Alone and in Combination with Cetirizine in the Prophylactic Treatment of Seasonal Allergic Rhinitis. Drug Invest 1994;8(4):225-233.

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FLONASE Product Overview

FLONASE allergy relief—the efficacy of prescription fluticasone propionate, with OTC benefits1

Prescription-Strength Fluticasone Propionate, Available OTC1

FLONASE—Gold-standard INS efficacy for more complete 24-hour allergy relief‡1,2,15-21

Read more about Flonase products

FLONASE SENSIMIST Allergy Relief

Children’s FLONASE SENSIMIST Allergy Relief

Children’s FLONASE Allergy Relief

Allergic Rhinitis Overview

Causes and Mechanisms

Patient care resources

Patient FSA / HSA Eligible Product

References

FLONASE allergy relief—the efficacy of prescription fluticasone propionate, with OTC benefits¹

Prescription-Strength Fluticasone Propionate, Available OTC¹

FLONASE—Gold-standard INS efficacy for more complete 24-hour allergy relief^‡1,2,15-21