Panadol Actifast

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Panadol Actifast pack shot

For fast relief1*

With 2x faster disintegration and absorption than standard paracetamol tablets, Panadol Actifast relieves pain fast1 and can even be taken on an empty stomach.2,3†

Figure showing faster disintegration time of Panadol Actifast

2X faster mean disintegration time1*

Gamma scintigraphic images (scinitigraphy is a form of radio-imaging or scanning that involves injecting a radioisotope that emits gamma rays into a patient’s vein, which are captured as images)4 of the stomach showed that Panadol Actifast disintegrated 2x faster than standard paracetamol tablets, whether patients were fasted or fed.1

Graph that shows Panadol Actifast is absorbed faster compared with standard paracetamol tablets

2X faster absorption with Panadol Actifast5,6*

Twenty-eight healthy volunteers were given standard paracetamol tablets and Panadol Actifast in a crossover study. Blood samples were taken at regular intervals and analysed by high-performance liquid chromatography.

The time taken to reach maximum dose (Tmax) of Panadol Actifast was significantly shorter than standard paracetamol tablets in both fasted and fed subjects.5

Graph showing time to pain relief for Panadol Actifast and standard paracetamol tablets

Pain relief ‡ 10 minutes faster7*

Panadol Actifast was shown to provide some pain relief 10 minutes faster than standard paracetamol. In a single centre randomised, double blind, single-dose study, the time to onset and the degree of pain relief were determined with either two Panadol Actifast tablets (n=90) or standard paracetamol tablets (n=90) administered to patients who had undergone dental extraction. The time to onset of meaningful pain relief was 30 minutes vs. 40 minutes for standard paracetamol.7

What can Panadol Actifast do for Brody?

Image of a patient pain free from headache

Brody wants to get rid of his headache fast

Brody is a young executive working his way up the corporate ladder. With long workdays and tight deadlines, it’s not surprising he sometimes suffers from headaches. He’s seen his doctor about it and was glad to hear that these were nothing more serious than tension type headaches, though it impacts his life and work at times.

Brody needs something that works fast to relieve his headaches when he gets them. He also wants something gentle for his stomach, as regular meal times aren’t part of his lifestyle.

Panadol Actifast offers Brody the fast relief he needs and is gentle to the stomach.

Recommend Panadol Actifast for fast relief

Panadol Actifast pack shot

Panadol Actifast

Release paracetamol even before it reaches the stomach.1 Does not compromise the stomach’s protective lining and can be taken even on an empty stomach or by those at risk of stomach ulcers.2,3†

Panadol Actifast product detail

  • Each tablet contains paracetamol 500 mg.

    Also includes excipients;Sodium Bicarbonate Pregelatinised starch, pregelatinised starch, povidone, potassium sorbate, magnesium stearate, microcrystalline cellulose, carnauba wax. Film coat: Opadry II Y-22-7719 white: titanium dioxide (E171), polydextrose, hypromellose, triacetin and macrogols.

  • Always read the label prior use.

    -Do not take more than 8 tablets (4000 mg) in 24 hours.

    -Do not take more frequently than every 4 hours.

    Panadol Actifast not recommended for children under 12 years of age.

    Do not take panadol Actifast in case of Known or previous history of hypersensitivity to paracetamol or other expedients.

    -Do not exceed the recommended dose.

    -This product contains Paracetamol. Do not take other Paracetamol containing medications.

    see your doctor if symptoms do not improve.

    Each tablet contains 173 mg of sodium (346 mg sodium per 2 tablet dose). To be taken into consideration by patients on a controlled sodium diet.

    The liver toxic effects of Panadol Actifast may be increased by the use of alcohol.

    The anticoagulant effect of warfarin and other coumarins may be enhanced by prolonged regular daily use of paracetamol with increased risk of bleeding; occasional doses have no significant effect.

    Pregnancy & breast feeding:

    Seek medical advice before taking this product if you are pregnant or breast feeding. - Human and animal studies with paracetamol have not identified any risk to pregnancy or embryo-foetal development or lactation or the breast-fed offspring. Paracetamol crosses the placental barrier and is excreted in breast milk.

    Overdose

    Paracetamol:

    Immediate medical management is required in the event of overdose for the risk of liver failure, even if symptoms of overdose are not present. In massive over dosage exceeding 10g of Paracetamol may cause liver failure. Early symptoms may include pallor, nausea, vomiting, (diaphoresis) and general malaise. Clinical and laboratory evidence of liver damage may not be apparent until 48 to 72 hours past ingestion.

    Overdose should be promptly treated by gastric lavage followed by intravenous N- acetylcysteine or methionine without waiting for the results of plasma paracetamol levels. General supportive measures must be available.

    Additional antidote therapy is normally considered in light of further plasma paracetamol levels and the time elapsed since ingestion. In all cases of suspected overdose, prompt medical attention is critical for adults as well as for children, even if you do not notice any signs or symptoms.

    Sodium bicarbonate:

    High doses of sodium bicarbonate would be expected to induce gastrointestinal symptoms including belching and nausea. In addition, high doses of sodium bicarbonate may cause hypernatraemia, electrolytes should be monitored and patients managed accordingly.

  • Body system Undesirable effect Frequency

    Blood and lymphatic system disorders

    		 Thrombocytopenia

    Very rare

    Immune system disorders

    Anaphylaxis

    Cutaneous hypersensitivity reactions including, among others, skin rashes, angioedema and Steven Johnson syndrome and toxic epidermal necrolysis

    Very rare

    Respiratory, thoracic and mediastinal disorders

    Bronchospasm in patients sensitive to aspirin and other NSAIDs.

    Very rare

    Hepatobiliary disorders

    Hepatic dysfunction

    Very rare

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