Use only in children aged 12 years and older. Oxymetazoline is not recommended for use in children aged 6 to 11 years, due to a lack of data on efficacy. It is not suitable for use in children under the age of 6.1
Oxymetazoline, like other sympathomimetic agents, should be used with caution in patients showing a strong reaction to adrenergic substances, such as signs of insomnia, dizziness, tremors, cardiac arrhythmias or elevated blood pressure.1
This product should be used with caution in patients with:1
- hypertension or cardiovascular disease
- hyperthyroidism
- diabetes mellitus
- phaeochromocytoma
- prostatic hypertrophy
- monoamine oxidase inhibitors (MAOI) treatment, or who have received them in the previous two weeks
- tri- and tetra-cyclic antidepressant treatment
There have been rare cases of posterior reversible encephalopathy (PRES)/reversible cerebral vasoconstriction syndrome (RCVS) reported with sympathomimetic drugs. Symptoms reported included sudden onset of severe headache, nausea, vomiting, and visual disturbances. Most cases improved or resolved within a few days following appropriate treatment. Oxymetazoline should be discontinued immediately and medical advice sought if signs/symptoms of PRES/RCVS develop.
As with other topical vasoconstrictors, this product should not be used for more than ten consecutive days: prolonged or excessive use may cause rebound congestion (rhinitis medicamentosa), nasal mucosa atrophy and tachyphylaxis.
Patients should consult a doctor if their symptoms do not improve.
Keep out of sight and reach of children.1
