Otrivin Plus: Xylometazoline and ipratropium

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Treats all symptoms
Long-lasting effect
Strong combination
Recommend Otrivin Plus
Product details

Immediate and long-lasting relief of nasal cold symptoms

Otrivin Plus nasal spray is recommended for active, busy individuals who need immediate and long-lasting relief from the worst nasal cold symptoms.^1-4

Treats the worst nasal symptoms all at once^1-4

Otrivin Plus provides symptomatic treatment of the worst nasal symptoms, such as blocked nose, rhinorrhoea and sinus pressure due to common colds.

Xylometazoline and ipratropium: Effective combination

A combination of two topical agents, to relieve patients’ worst cold symptoms at once:

Xylometazoline hydrochloride (0.05%):

A sympathomimetic agent, provides rapid and long-lasting relief (within 5-10 minutes and for up to 6-8 hours) of nasal congestion^3-5
It improves nasal airflow, reduces mucus hypersecretions and relieves sinus pressure^6-9

Ipratropium bromide (0.06%):

An anticholinergic agent that reduces watery discharge from nasal mucosa (rhinorrhoea)^2,4,10,11

Recommend Otrivin Plus to your patients for immediate and long-lasting relief from the worst nasal cold symptoms

Otrivin Plus (Xylometazoline hydrochloride 0.05%+ ipratropium bromide 0.06%)

For patients who are looking for rapid and effective relief of nasal cold symptoms^.1-4

Otrivin Plus product details

Ingredients

Active ingredients:

1 ml contains 0,5 mg xylometazoline hydrochloride and 0,6 mg ipratropium bromide.

Inactive ingredients:

Disodium edetate, glycerol (85 %), hydrochloric acid, sodium hydroxide, and purified water.

Otrivin Plus: Immediate and long-lasting relief of nasal cold symptoms^1-4

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References

OTRIVIN PLUS Nasal Metered-dose Spray (Solution) package insert February 2021.
Eccles R et al. Am J Rhinol 2007; 21:40–45.
Eccles R et al. Am J Rhinol 2008; 22:491–496.
Hayden FG et al. Ann Intern Med 1996; 125:89–97.
Clarke RW et al. Clin Otolaryngol Allied Sci 1995; 20:72–73.
Acute Sinusitis. Cleveland Clinic. Available at: http://my.clevelandclinic.org/services/head-neck/diseases-conditions/hic-acute-sinusitis. (Accessed January 2019).
Gwaltney JM et al. N Engl J Med 1994; 330:25–30.
Gwaltney JM. Am J Med 2002; 112:13S-18S.
Sperber SJ et al. Arch Fam Med 2000; 9:979–985.
Ostberg B et al. Rhinology 1997; 35:58–62.
Kim KT et al. Ann Allergy Asthma Immunol 2005; 94:73–9.

S2 OTRIVIN PLUS Nasal Metered-dose Spray (Solution). Each 1 ml contains 0,6 mg of ipratropium bromide and 0,5 mg of xylometazoline hydrochloride. (Preservative-free). Reg. no.: 46/16.1/0819..

Applicant: Haleon South Africa (Pty) Ltd. 11 Hawkins Avenue, Epping Industria 1, Cape Town, 7450

Company reg. no.: 2014/173930/07. For full prescribing information refer to the professional information approved by the medicines regulatory authority.

Always read label prior to use.

For any further information, including safety and adverse reactions, please contact the Haleon Hotline on 0800 007 018 or mystory.za@haleon.com.

Trademarks are owned by or licensed to the Haleon group of companies.

This site is intended for RSA healthcare professionals only.

© 2024 Haleon group of companies or its licensor. All rights reserved. Trademarks are owned by or licensed to the Haleon group of companies. This website is operated by Haleon South Africa (Pty) Ltd. 17 Muswell Road South, Block D, Wedgefield, Phase 2, Bryanston, Johannesburg, 2191, South Africa. Reg. No: 2014/173930/07. For any further information, including Human Safety Information (Adverse events/Product Quality Complaints) please contact the Haleon on 0800 007 018 or mystory.za@haleon.com. Always read the label, the leaflet or carton for full use instructions before use.

PM-ZA-NOBR-20-00013

PM-ZA-OTRI-23-00019Date of preparation: October 2024