Nicotinell - nicotine replacement therapy (NRT)

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Quitting smoking is an uphill battle: tilt the odds in your patients’ favour with Nicotinell

Quitting is frustratingly hard and knowing which Nicotine Replacement Therapy (NRT) products are the most suitable to recommend can be difficult. Approximately 70-90% of smokers say that withdrawal symptoms and cravings are the reason why they do not quit smoking.1

NRT products are used to address physical cravings by providing a measured dose of nicotine, without the harmful ingredients found in tobacco. By providing nicotine in this way, the patient’s cravings can be reduced.

Image of the 5 withdrawal symptoms of quitting

Help your patients win the fight against cravings with the Nicotinell range

NRT allows patients to decrease their therapeutic nicotine intake, as both the physical and behavioural dependency is reduced.2,3

How NRT works

Cravings can be hard to overcome with willpower alone and using NRT products, such as Nicotinell Patch, Gum or Lozenge delivers lower levels of therapeutic nicotine without the 7000 other chemicals found in cigarette smoke.

By reducing the physical symptoms from smoking cessation, NRT enables the customer to focus more on the emotional aspect of quitting.1 NRT helps manage withdrawal symptoms, which manifest within the first 1-2 days, peak within the first week and gradually dissipate over 3-4 weeks.4

Patch and lozenge packshot

How to recommend combination therapy

By combining Nicotinell Patch with Nicotinell 1mg Lozenge helps ensure your patients cravings can be managed effectively. When quitting, certain situations can lead to additional cravings e.g., after meals, when out for a drink or during times of stress.5

The discreet patch delivers constant levels of nicotine throughout the day. The lozenge can then be recommended for use when cravings hit to provide an additional nicotine ‘boost’.

By combining Nicotinell Patch with Nicotinell 1mg Lozenge you can boost your patient’s chance of quitting by up to 60% compared to using a single NRT format.6,7

  • Craving control on waking

    Patient picking up patch from shelf

    Nicotinell Patch

    Is your customer in the habit of smoking on waking? Do they have concerns about strong morning cravings overcoming their willpower? Nicotinell patches contain enough nicotine protection for up to 24 hours when customers stop smoking.

    By using the patches for 24 hours, customers will have nicotine in their blood when they wake up, so they’ll be ready to face the morning cravings more easily.

    Nicotinell patches are available in three strengths: 7 mg, 14 mg and 21 mg.

  • A targeted nicotine boost when cravings hit

    Patient picking up patch and lozenge from shelf

    Nicotinell Gum and Lozenges

    Do your customers find certain situations trigger cravings? Are they concerned about the need to replace a ‘cigarette moment’ to boost their nicotine intake?

    Nicotinell Medicated Chewing Gum (nicotine) offers rapid relief from sudden cravings and is available in 2mg and 4mg strength and fruit or mint flavours.

    Nicotinell Compressed Lozenge (nicotine) starts to work in minutes and offers rapid craving relief. They can be used discreetly for situations such as work where chewing gum may not be appropriate. Nicotinell Lozenges are available in 1mg and 2mg strength and have a mint flavour.

The Nicotinell Product Range – usage and dose

Nicotinell Patch pack-shot

Nicotinell Patch

Up to 24-hour nicotine craving relief.

Step 1 – >20 cigarettes a day: start with 21mg patch every day for 3-4 weeks

Step 2 – <20 cigarettes a day start with 14mg patch every day for 3-4 weeks

Customers who started on step 1 should switch to 14mg patch for another 3-4 weeks

Step 3 – customers should finish with the 7mg patch every day for 3-4 weeks

Nicotinell Gum pack-shot

Nicotinell Medicated Chewing Gum

Rapid relief from sudden cravings.

Light smokers (<20 cigarettes a day) – 2mg gum

Moderate smokers (20-30 cigarettes a day) – 2mg or 4mg gum

Heavy smokers (>30 cigarettes a day) – 4mg gum (also suitable for those who have previously been unsuccessful quitting with NRT)

Nicotinell Lozenge pack-shot

Nicotinell Compressed Lozenge

Provides rapid craving relief.

Light smokers (<20 cigarettes a day) – 1mg lozenge

Moderate smokers (20-30 cigarettes a day) – 1mg or 2mg lozenge

Heavy smokers (>30 cigarettes a day) – 2mg lozenge (also suitable for those who have previously been unsuccessful quitting with NRT)

Nicotinell Product Information

  • Product Information

    Nicotinell Mint 2mg/4mg medicated chewing gum, Nicotinell Fruit 2mg/4mg medicated chewing gum (nicotine polacrilin). Nicotinell TTS 10, Nicotinell TTS 20, Nicotinell TTS 30 (nicotine). Nicotinell Mint 1mg/2mg Compressed Lozenges (nicotine bitartrate dihydrate).

    Indications: Treatment of nicotine dependence, as an aid to smoking cessation.

    Dosage and method of use: Gum: Adults and elderly: Chew one piece of gum when urge to smoke is felt. Normally 8 to12 pieces per day, up to a maximum of 24 pieces of 2mg gum per day or 15 pieces of 4mg gum per day. Do not use more than 1 gum per hour. After 3 months, gradually cut down the gum usage. The 4mg gum is for those with a strong nicotine dependency. Adolescents (12 to 17 years): As for adults but seek medical advice if more than 12 weeks treatment required. Paediatric population: Not to be used by children under 12 years Patch: Adults: For those smoking ≥20 cigarettes a day: Nicotinell TTS30 (Step 1) once daily. Those smoking <20 start with Nicotinell TTS20 (Step 2) once daily. Reduce nicotine dose over treatment periods of 3 to 4 weeks by reducing patch strength in stepwise fashion. Use continuously for three months, if abstinence not achieved after 3 months further treatments may be recommended. Adolescents (12 to 17 years): Patients under the age of 18 years should seek medical advice before using the product and if treatment is required for longer than 10 weeks. Lozenge: Smoking cessation: Stop smoking completely during treatment. Suck one lozenge slowly. Normally, 8 to 12 lozenges per day, max. Maximum of 24x1mg lozenges per day or 15x2mg lozenges per day. After 3 months, gradually cut down the usage. The higher strength lozenge is for those with a strong nicotine dependency. Smoking reduction: Use to prolong smoke-free intervals to reduce smoking. Gradually replace cigarette number with lozenge. If a cigarette reduction of ≥50 % per day is not achieved after 6 weeks, or quit attempt not made within 6 months of starting treatment seek medical advice. Start quit attempt once ready but no later than 4 months after treatment starts. Gradually reduce lozenge number. Not generally recommended for regular use beyond 6 months. Combination treatment: For when treatment fails with lozenge alone, 1mg lozenge and patch used together for those smoking >20 cigarettes a day, recommended to seek HCP advice. 2mg lozenge not licensed for combination therapy. Start with one patch 21mg/24 hours plus 1mg lozenge (generally 5-6 pieces per day). Max 15 lozenges a day. Treat for 6-12 weeks, then gradually reduce nicotine dose by either 1) reducing patch strength sequentially at 3-6 weeks intervals, then gradually reducing number of lozenges. OR 2) discontinuing use of patches and gradually reducing number of lozenges. Alternate patch application site to avoid skin irritation. Max treatment duration is 9 months. Paediatric population: Not to be used by children under 12 years. Not to be used by adolescents 12-17 years of age without prescription from a healthcare professional.

    Contraindications: Known hypersensitivity to nicotine or any of the excipients. Use by non-smokers. Patch and gum: use by occasional smokers. Patch: diseases of the skin.

    Precautions: Use with caution in patients with: recent myocardial infarction, unstable or worsening angina including Prinzmetal's angina, severe cardiac arrhythmias, uncontrolled hypertension, or recent cerebrovascular accident who are considered to be haemodynamically unstable, history of epilepsy or those taking anti-convulsant therapy, diabetes mellitus, hyperthyroidism, pheochromocytoma, moderate to severe renal and/or hepatic impairment, active oesophagitis, oral and pharyngeal inflammation, gastritis, gastric/peptic ulcer. Gum: Not recommended for those with jawbone joint problems or denture wearers. May loosen fillings or dental implants. Do not use in patients with hereditary conditions of fructose intolerance. Contains butylhydroxytoluene which may cause irritation to the mucous. Patch: Have a history of dermatitis. Discontinue use if a severe or persistent skin reaction, including allergic reaction, occurs. Nicotinell TTS contains aluminium and should be removed prior to undergoing defibrillation, MRI or cardioversion procedures. Lozenge: Use with caution in patients with: hypertension, stable angina pectoris, cerebrovascular disease, occlusive peripheral arterial disease and heart failure. Contain aspartame, may be harmful to those with phenylketonuria. Do not use in patients with hereditary conditions of fructose intolerance.

    Side effects: See SPCs for full details. Gum: Common: nausea, salivary hypersecretion, jaw muscle ache and dyspepsia. Lozenge: Very common: nausea. Common: abdominal pain, insomnia, cough. Gum and Lozenge: Common: flatulence, stomach discomfort, stomatitis, dizziness, headache, hiccups, vomiting, diarhhoea, constipation, dry mouth, oral discomfort and pain, pharyngitis and pharyngolaryngeal pain. Patch: Very common: application site reactions, nausea, insomnia, abnormal dreams, headache, dizziness. Common: agitation, anxiety, nervousness, cough, pharyngitis, dyspnoea, abdominal pain, upper dyspepsia, motor dysfunction, tremor, palpitations, dry mouth, increased sweating, myalgia, asthenia, fatigue, stomatitis, oesophagitis, arthritis, diarrhoea.

    Product licence number, legal category, pack size and RSP (excl. VAT): Nicotinell Fruit 2 mg Medicated Chewing Gum, PL 44673/0122: GSL, 96: £16.31, 204: £30.90; Nicotinell Fruit 4 mg Medicated Chewing Gum, PL 44673/0123: GSL, 96: £20.26; Nicotinell Mint 2 mg Medicated Chewing Gum, PL 44673/0126: GSL, 96: £16.31, 204: £30.90; Nicotinell Mint 4 mg Medicated Chewing Gum, PL 44673/0127: GSL, 96: £20.26; Nicotinell TTS 10, PL 44673/0128: GSL, 7: £15.66; Nicotinell TTS 20, PL 44673/0129: GSL, 7: £16.15; Nicotinell TTS 30, PL 44673/0130: GSL, 7: £17.12, 21: £42.09; Nicotinell Mint 1 mg Compressed Lozenges, PL 15545/0003: GSL,12: £3.13, 96: £18.00, 144: £22.68, 204: £25.19, Nicotinell Mint 2 mg Compressed Lozenges, PL 15545/0004: GSL, 96: £20.93, 144: £26.46, 204: £29.48.

    PL holder: Gums and Patches: Haleon UK Trading Limited, The Heights, Weybridge, Surrey, KT13 0NY, U.K. Lozenges: GlaxoSmithKline Dungarvan Limited, Knockbrack, Dungarvan, County Waterford, Ireland.

    Date of preparation: Jan 2024.

Help your patients quit smoking for good with Nicotinell

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