Voltarol Max Strength Pain Relief 2.32% Gel (Diclofenac diethylammonium)

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Voltarol Max Strength Pain Relief 2.32% Gel
Diclofenac gets deep into the joint area¹
83% more diclofenac in the skin layers in 24 hours vs 4 hours^{†^9}
Lowest NNT
Product Information

Diagram showing the concentrations of diclofenac reaching the various tissues beneath the skin of the knee following topical application

Voltarol Max Strength Gel – clinically proven to demonstrate deep tissue penetration^† into the joint¹

Formulation matters when it comes to topical pain relief to deliver the active ingredient efficiently into the skin layers in order to reach the site of pain.²

Voltarol Max Strength Pain Relief 2.32% Gel with the potent active ingredient diclofenac:

Contains oleyl alcohol, a permeation enhancer which delivers up to 3x greater skin penetration^†* for effective delivery of diclofenac to the site of pain and inflammation³
Has a double concentration formula* to provide up to 12 hours uninterrupted pain relief⁴
Indicated for osteoarthritis in addition to sprains, strains, back pain and joint pain

Learn more about the Voltarol formulation and access videos and resources to support your care of patients with musculoskeletal pain by visiting the Voltarol Science Academy.

^†in vitro study*vs 1.16% diclofenac gel

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Voltarol Max Strength Pain Relief 2.32% Gel

Diclofenac gets deep into the joint area¹

After topical administration, diclofenac is distributed to the subcutaneous tissues, muscle, synovial tissues and synovial fluid, the latter tissues typically being most likely to be driving joint pain.⁵ Its chemical properties support retention within the joint where it is needed, rather than the blood stream.^5,6

Voltarol Max Strength Pain Relief 2.32% Gel is specially formulated to help the anti-inflammatory ingredient get through the skin.¹ It contains a permeation enhancer for increased delivery of diclofenac through the skin.¹*

The deep penetration of Voltarol Max Strength Pain Relief 2.32% Gel makes it suitable for the treatment of joint pain related to trauma of the tendons, ligaments, muscles and other joint tissues as well as localised soft-tissue rheumatism and osteoarthritis.

*vs. diclofenac 1.16% gel. In vitro study.

Image of the layers of the skin to demonstrate the fact that there is 83% more diclofenac in the skin layers in 24 hours vs 4 hours based on in vitro study

83% more diclofenac in the skin layers in 24 hours vs 4 hours^{†^9}

Voltarol Gel is intelligently formulated to efficiently deliver diclofenac in sufficient concentrations to achieve desired therapeutic effects without compromising safety.⁷ It contains a permeation enhancer for up to 3x greater skin penetration.*^†1

Voltarol Gel delivers diclofenac into inflamed tissues by forming a reservoir which gradually expands throughout 24 hours. There is 83% more diclofenac in the skin layers in 24 hours vs 4 hours.^†^⁹

*vs 1.16% gel^{^}Max daily dose applied in one go, semi-quantitative ToF-SIMS evaluation†in vitro study

The lowest number-needed-to-treat (NNT) for Voltarol Gels* in a Cochrane Review of topical NSAIDs vs placebo¹⁰

A Cochrane Review of 61 studies of topical NSAIDs compared with placebo (>8000 patients) reported that Voltarol Gels* have the lowest NNT (1.8) of topical NSAIDs in acute musculoskeletal pain, including topical ibuprofen (3.9).^†10

This means that for every single patient you recommend Voltarol Gels to, over other topical NSAIDs, you have a better chance of giving them the significant pain relief that helps get them back on their feet and enjoying life again.¹⁰

*1.16% and 2.32% Voltarol Gel formulations included in the review.^†vs topical ibuprofen, ketoprofen benzydamine, piroxicam and indomethacin.

Lower systemic exposure vs oral NSAIDs

GIF animated image of a body outline showing the application of topical gels directly to the site of pain in the knee.

Low systemic absorption, for a lower risk of systemic side effects^5,11

Voltarol Max Strength Pain Relief 2.32% Gel has a low systemic exposure^3,12meaning a reduced risk of systemic side effects and drug–drug interactions.⁵

That includes a reduced systemic side-effect risk vs oral NSAIDs (e.g. gastrointestinal events).*^13,14

Recommend Voltarol Max Strength Pain Relief 2.32% Gel for effective relief from joint pain with a reduced risk of systemic side effects.

*There is an increased risk of mild dermatological side effects (e.g. skin irritation) with topical diclofenac, but this is generally non-serious and reversible

Image of a man and a woman walking through a hillside scene

Nick wants to relieve pain and regain mobility by easing joint stiffness

Nick sometimes wakes in the morning with stiffness and pain in his knees but likes to get moving.

He is looking for an analgesic that provides lasting relief so he does not need to take it every few hours. He has taken oral medications in the past but is keen to see if there is an option which treats the site of pain directly.

He wants sustained relief from his pain so that he can do the things he enjoys such as hiking and cycling.

Voltarol Max Strength Pain Relief 2.32% Gel is clinically proven to demonstrate deep penetration into the joint¹ and provides clinically proven joint pain relief.⁴ It improves joint mobility and reduces time to return to normal functioning.⁴ It offers Nick a convenient, twice-daily application, without the worry associated with drug-drug interactions.

For further information refer to Product Information at the bottom of the page.

Recommend Voltarol Max Strength Pain Relief 2.32% Gel to your patients for up to 12 hours of uninterrupted pain relief.⁴