Indications: Mild to moderate pain including headache, migraine, neuralgia, toothache, sore throat, period pains, symptomatic relief of sprains, strains, rheumatic pain, sciatica, lumbago, fibrositis, muscular aches and pains, joint swelling and stiffness, influenza, feverishness and feverish colds. Dosage: Adults and young persons aged 16 and over: 2 tablets every 4 hours to a maximum of 8 tablets in 24 hours. Do not give to children aged under 16 years, unless specifically indicated. Migraine: not recommended for those under 18 years of age. Elderly: use with caution in those more prone to adverse events. Contraindications: Hypersensitivity to the active ingredients or to any other excipients. Use in patients in whom asthma, bronchospasm, angioedema, urticaria, or acute rhinitis are precipitated by aspirin or other non-steroidal anti-inflammatory drugs (NSAIDs). Those with peptic ulceration and those with a history of peptic ulceration; history of upper gastrointestinal bleeding or perforation, related to previous NSAID therapy, history of haemophilia, hypothrombinaemia or other clotting disorders, renal failure (GFR < 15mL/min/1.73m2), hepatic failure, third trimester of pregnancy, children under 16 years and when breast feeding (possible risk of Reye's Syndrome). Warnings and precautions: Do not use with any other paracetamol containing products, or other systemic NSAIDs, including cyclooxygenase-2 selective inhibitors. Do not take if you have a stomach ulcer or rare hereditary problems of galactose intolerance; the Lapp lactose deficiency or glucose-galactose malabsorption. Avoid excessive intake of caffeine. Serious hypersensitivity reactions or anaphylaxis can occur, bronchospasm may be precipitated in patients suffering from or with a previous history of asthma, allergic disease or nasal polyps. Cases of hepatic dysfunction/failure have been reported in patients with depleted glutathione levels, such as those who are severely malnourished, anorexic, have a low body mass index or are chronic heavy users of alcohol or have sepsis. Use with caution in elderly patients more prone to adverse events. If symptoms persist speak to a doctor. Contains aspartame, which may be harmful for people with phenylketonuria. Aspirin: Should not be given to children under 16 years, particularly during or immediately after chickenpox, influenza, or other viral infections, unless prescribed by a physician or specifically indicated. Decreases platelet adhesiveness and increases bleeding time. Patients should report any unusual bleeding symptoms to their physician. May induce haemolysis or haemolytic anaemia in patients with glucose-6-phosphate dehydrogenase (G6PD) deficiency. Use with caution in patients with uncontrolled hypertension (in whom target blood pressure has not been achieved), impaired renal or hepatic function, in patients who are dehydrated, suffering from diabetes mellitus or who have or have a history of gout. Gastrointestinal bleeding, ulceration or perforation , which can be fatal, have been reported with all NSAIDs and may occur at any time during treatment, with or without warning symptoms or a previous history of serious GI events. Generally, more serious consequences in the elderly. Paracetamol: may increase the risk of metabolic acidosis in patients with glutathione depleted states. Caution if used at therapeutic doses for a prolonged period or administered concomitantly with flucloxacillin due to increased risk of high anion gap metabolic acidosis (HAGMA), particularly in patients with severe renal impairment, sepsis, malnutrition and other sources of glutathione deficiency (e.g. chronic alcoholism). If suspected, discontinue use promptly and monitor closely, including measurement of urinary 5-oxoproline. Side effects: Very rare: Aspirin-exacerbated respiratory disease, thrombocytopenia, anaphylaxis, cutaneous hypersensitivity reactions, bronchospasm, hepatic dysfunction. All other side effects have an unknown frequency, please refer to the SPC for full details. Legal category: GSL Product licence number: PL 44673/0200. MAH: Haleon UK Trading Limited, The Heights, Weybridge, Surrey, KT13 0NY, U.K. RRP (excl VAT): 12s: £3.74. Text prepared: Jan 2026