Study Summary: Efficacy & Safety of Diclofenac Gel for Knee OA

Diclofenac Gel for Knee OA Clinical Study Summary

Download our study summary to learn more about how treating knee OA with diclofenac sodium gel (DSG 1%) achieved clinically significant improvements in pain and physical function compared to vehicle over 12 weeks with low exposure and favorable tolerability.

Study objective & methodology:

A 12-week, randomized, double-blind, vehicle-controlled, parallel-group, multicenter study to assess the efficacy and safety of topical DSG 1% in mild to moderate symptomatic knee osteoarthritis.


Patients treated with DSG 1% exhibited significant improvement in:

  • Mean WOMAC pain index
  • Mean WOMAC physical function
  • Mean global rating of disease
  • Reductions in pain on movement at Week 4 compared to vehicle

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