Study Summary: Efficacy & Safety of Diclofenac Gel for Knee OA
Download our study summary to learn more about how treating knee OA with diclofenac sodium gel (DSG 1%) achieved clinically significant improvements in pain and physical function compared to vehicle over 12 weeks with low exposure and favorable tolerability.
Study objective & methodology:
A 12-week, randomized, double-blind, vehicle-controlled, parallel-group, multicenter study to assess the efﬁcacy and safety of topical DSG 1% in mild to moderate symptomatic knee osteoarthritis.
Patients treated with DSG 1% exhibited signiﬁcant improvement in:
- Mean WOMAC pain index
- Mean WOMAC physical function
- Mean global rating of disease
- Reductions in pain on movement at Week 4 compared to vehicle
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