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Diclofenac
Iodex Ultragel (globally known as Voltaren) products contain diclofenac – a potent anti-inflammatory ingredient1
Diclofenac is the active ingredient in topical and oral Iodex Ultragel (globally known as Voltaren) products that relieves pain by targeting inflammation.1–4
Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) that targets key steps in inflammatory cascades.
Acts through cyclo-oxygenase-2 (COX-2) inhibition, striking inflammation at its source
Learn how diclofenac reduces inflammation by inhibiting prostaglandin biosynthesis through action on the COX enzymes with selectivity for COX-2, and inhibiting phospholipase A2 activity to reduce the production of inflammatory leukotrienes.1,2,4
Diclofenac is a potent anti-inflammatory agent1
Its effect on the COX-2 enzyme means that, unlike non-NSAID medications such as paracetamol, diclofenac not only provides pain relief but also treats inflammation – a root cause of pain.2,4
Diclofenac, an NSAID (and therefore in the same drug class as ketoprofen and ibuprofen), shows marked potency in its inhibition of the COX-2 enzyme.5
Diclofenac targets inflammation to fight pain at its source
Diclofenac-containing products
Iodex Ultragel 1.16% Emulgel
Iodex Ultragel 1.16% Emulgel contains 1.16% diclofenac diethylamine and is an effective alternative to over-the-counter oral analgesics.2,6,7
Indicated for relief of pain and swelling in soft-tissue injuries and localised forms of soft-tissue rheumatism, and relief of non-serious arthritis of the knee or fingers.2
See the evidence for Iodex Ultragel.
Diclofenac – a potent anti-inflammatory ingredient1
Skin Hydration and cooling effect produced by the Voltaren vehicle gel
Evidence based review in more than 3000 patients shows topical Diclofenac effective & well tolerated in painful and inflammatory conditions
Cochrane review on acute and chronic pain in adults
Topical analgesics for acute and chronic pain in adults- an overview of Cochrane review.
Voltaren efficacy in acute neck pain
Efficacy and Safety of Diclofenac diethylamine 1.16% gel in acute neck pain
