Calpol Tablets

Calpol Tablets pack shot

Advanced absorption1 for fast pain relief 2*

The revolutionary Optizorb technology allows Calpol Tablets to begin disintergrating in 5 minutes1 and start to relieve pain within 15 minutes with 2 tablets (1000 mg dose).3 May be suitable for special populations including those with cardiovascular disease,4 heart conditions,5-7 hypertension,6 the elderly8 and diabetics.9

Optizorb technology

Graph showing efficacy of paracetamol vs NSAID <24 hours

Calpol in musculoskeletal pain

Calpol is as effective at releasing pain compared to NSAIDs at 24 hours, days 1-3 and at day 7.10 It was also found to be as effective as NSAIDs in treating acute body pain in people with musculoskeletal injuries.11

Graph showing difference between paracetamol and NSAID for return to function within or after seven days

No difference between Paracetamol and NSAID for return to function within or after seven days.10

Graph showing how Calpol Tablets is absorbed better than standard paracetamol

Calpol Tablets absorbs twice as fast12†

This was a pharmacokinetic study of 76 healthy adults of replicate dosing of Calpol Tablets or standard paracetamol tablets (1000 mg dose) administered on 4 separate days.12 The average concentration of paracetamol in plasma at 10, 20 and 30 minutes for Calpol Tablets was 1.62; 3.26; 4.93 vs. 0.69; 1.8; 2.82 for standard paracetamol tablets. This means that the concentration of paracetamol at 10, 20 and 30 minutes in subjects taking Calpol Tablets was 134%, 81% and 75% higher than those that ingested standard paracetamol tablets.12

Optizorb technology

Recommend Calpol Tablets for faster relief compared to standard paracetamol.

Calpol Tablets pack shot

Calpol Tablets

Disintegrates faster and available for absorption quicker1* than standard paracetamol to provide pain relief.

Calpol Tablets product details

  • Each film-coated tablet contains 500 mg paracetamol.

    The other ingredients are: pregelatinized maize starch, calcium carbonate, alginic acid, crospovidone, povidone (K-25), magnesium stearate, colloidal anhydrous silica, titanium dioxide, hypromellose 3cP, hypromellose 6cP, macrogol, polysorbate 80, carnauba wax.

    As preservative: Blend of sodium parabens 1.35 mg / tablet (containing sodium methylparahydroxybenzoate, sodium ethyl parahydroxybenzoate; sodium propyl parahydroxybenzoate).

    Sugar Free.

  • Do not take CALPOL TABLETS:

    • If you are allergic to paracetamol or any of the ingredients in the tablet.
    • If you have severe liver problems.

    Take special care with CALPOL TABLETS:

    • Do not exceed the recommended daily dose, as it may cause serious harm to your liver.
    • Do not use CALPOL TABLETS if you are taking any other prescription or non-prescription medicines containing paracetamol to treat pain, fever, symptoms of cold and flu, or to aid sleep.
    • Check with your doctor before use if you:
    1. Have liver or kidney problems
    2. Are underweight or malnourished
    3. Regularly drink alcohol

    You may need to avoid using CALPOL TABLETS altogether or limit the amount of paracetamol you take, as this may increase the risk of paracetamol-related liver damage.

    • Check with your doctor before use if you have a severe infection, are severely malnourished, severely underweight or are a chronic heavy alcohol user as this may increase the risk of metabolic acidosis. Signs of metabolic acidosis include:
    1. Deep, rapid, difficult breathing
    2. Feeling sick (nausea), being sick (vomiting)
    3. Loss of appetite

    Contact a doctor immediately if you get a combination of these symptoms.

    • Do not use continuously for more than 10 days without consulting your doctor or 3 days for your child.
    • Consult your doctor if no relief is obtained with the recommended dosage.
  • Body system

    Undesirable effect

    Blood and lymphatic system disorders

    Thrombocytopenia, Agranulocytosis, leucopenia, pancytopenia, neutropenia anemia

    Immune system disorders


    Cutaneous hypersensitivity reactions including among others, skin rashes, angioedema and Steven Johnson syndrome and toxic epidermal necrolysis

    Respiratory, thoracic and mediastinal disorders

    Bronchospasm in patients sensitive to aspirin and other NSAIDs

    Hepatobiliary disorders

    Hepatic dysfunction

    Renal and urinary disorders Renal colic, renal failure and sterile pyuria
    Gastrointestinal disorders Pancreatitis

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Optizorb formulation icon

Calpol Optizorb technology

Discover more about this revolutionary technology that allows delivery of paracetamol fast14 and effectively15 when it is needed most.

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Man with a fever


Paracetamol is a well-known antipyretic. Learn more about fever and how to manage it.

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Expert tips for counseling patients

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