Panadol 500mg Film Coated Tablets paracetamol (for pharmacists only)

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Panadol 500mg Film Coated tablets pack shot

Fast absorption for fast pain relief vs standard paracetamol tablets

For pharmacists: The unique Optizorb technology allows Panadol to begin dissolving in 5 minutes1 and start to relieve pain within 15 minutes with 2 tablets (1000 mg dose).2

Optizorb technology

Image of a tablet with the ingredients alginic acid, calcium carbonate and crospovidone highlighted

Three super disintegrants speed up tablet disintegration

Panadol 500mg tablets are formulated with three super disintegrants to speed up the tablet disintegration – alginic acid, crospovidone and calcium carbonate.

After 5 minutes: Tablets disintegrate significantly faster than standard paracetamol tablets and are beginning to pass from the stomach to the small intestine where they can be absorbed into the bloodstream.1

After 20 minutes: Fully disintegrated and available for absorption from the intestine, while standard paracetamol tablets have yet to leave the stomach.1

Graph showing % coefficient of variability for Panadol with Optizorb vs standard paracetamol tablets for inter-subject variability and intra-subject variability

Delivers more consistent pain relief vs standard paracetamol

Panadol with Optizorb delivers more consistent and predictable pain relief by:1-3

  • Absorbing fast – up to 25% faster than standard paracetamol tablets
  • Significantly reduced individual variations (p<0.0001)

Recommend Panadol for fast and effective pain relief

Panadol 500mg Film Coated Tablets (paracetamol) pack shot

Panadol 500mg film-coated tablets (paracetamol)

Panadol 500mg Tablets start releasing paracetamol in 5 minutes1 and can start to relieve pain in just 15 minutes compared to standard paracetamol.2

Panadol product details

  • Product information

    Please consult the summary of product characteristics for full product information.

    Panadol 500mg Film Coated Tablets (paracetamol). Indications: Short-term management of headaches, musculoskeletal disorders, menstrual pains, toothache, symptoms of colds and flu, mild to moderate pain associated with diagnosed osteoarthritis. Dosage: Adults (including the elderly) and children 16 years and over: 1-2 tablets, up to 4 times daily, as required. Children aged 10-15 years of age: 1 tablet, up to 4 times daily as required. Do not give to children for more than 3 days without consulting a doctor. Not recommended for children under 10 years. Max 4 doses in 24 hours. Minimum dosage interval is 4 hours. Contraindications: Hypersensitivity to paracetamol or any of the other ingredients. Precautions: Do not use with any other paracetamol-containing products. Cases of hepatic dysfunction/failure have been reported in patients with depleted glutathione levels. Those diagnosed with liver or kidney impairment must seek medical advice before use. Caution, regarding paracetamol, if used at therapeutic doses for a prolonged period or administered concomitantly with flucloxacillin due to increased risk of high anion gap metabolic acidosis (HAGMA), particularly in patients with severe renal impairment, sepsis, malnutrition and other sources of glutathione deficiency (e.g. chronic alcoholism). If suspected, discontinue use promptly and monitor closely, including measurement of urinary 5-oxoproline. Do not exceed the stated dose. If symptoms persist consult a doctor. Prolonged use, except under medical supervision, may be harmful. Side effects: Very rare: Thrombocytopenia, bronchospasm, hepatic dysfunction, hypersensitivity reactions including anaphylaxis and skin rash, angioedema, Stevens-Johnson syndrome, Toxic Epidermal Necrolysis, serious skin reactions. Not known: High anion gap metabolic acidosis. Legal Category: 12 Tablets GSL; 24 Tablets Pharmacy Only. MA Number: PA 678/107/1. MA Holder: Haleon Ireland Limited, Clocherane, Youghal Road, Dungarvan, Co. Waterford, X35 Y983, Ireland. Text prepared: March 2026. Further information available on request.

    Contains Paracetamol. Always read the label/leaflet.

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Panadol Optizorb technology

For pharmacists: Discover more about the Optizorb technology that allows delivery of paracetamol fast1 and effectively when it is needed most.

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Panadol Science Academy

For pharmacists: Panadol Science Academy includes information on pain and the analgesic action of paracetamol. Find out how to manage patients' pain on Haleon HealthPartner.

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