Allergic Rhinitis Overview
At GSK we are committed to helping your patients with respiratory allergies feel better and to reducing their symptom burden and adverse consequences.
Allergic rhinitis (AR) is defined as an IgE antibody-mediated, inflammatory disease characterized by one or more of the following symptoms: nasal congestion, rhinorrhea (runny nose), and sneezing and itching2.
There are several AR classification characteristics that can be helpful to determine appropriate patient treatment strategies, including2:
- Temporal pattern and context of exposure to a triggering allergen: a) Seasonal (eg, pollens) or perennial (year-round exposures such as house dust mites), or b) Episodic environmental (from allergen exposures not normally encountered in the patient’s home or occupational environment, eg, visiting a home with pets not present in an individual’s home)
- Frequency and duration of symptoms
- Severity of symptoms
AR has traditionally been categorized as seasonal AR (SAR) or perennial AR (PAR), both of which are conditions recognized as having similar pathophysiologic and end-organ manifestations. In general, the differences between the two conditions are primarily based on the causes and duration of disease.2
Third type of allergic rhinitis, vasomotoric AR (VAR) is an inflammation of the nasal mucosa of unknown cause.
Quality of life impact
Many patients will “suffer in silence” without talking about their symptoms. They may be purposefully diminishing their allergy symptoms and the impact they have on their quality of life for a variety of reasons12:
- They believe allergies aren’t that serious or are not a “real disease,” but more of a nuisance13
- They may not know that while allergies may seem benign, they can still significantly impact their quality of life12
- They may be unaware that untreated allergies can increase the risk for more serious diseases, such as anaphylaxis, asthma, sinusitis, altered mood, and cognitive impairment12,14
Patients may not recognize some symptoms as being related to allergies. In addition to these more obvious symptoms, there are a few other surprising symptoms that may be due to allergies, namely5:
- Chronic fatigue
- Upper respiratory infection
- Sinus infection
- Sleeping problems
- Difficulty concentrating
- Lack of exercise endurance