Voltaren Science - Diclofenac

Acts through cyclo-oxygenase-2 (COX-2) inhibition, striking inflammation at its source

Learn how diclofenac reduces inflammation by inhibiting prostaglandin biosynthesis through action on the COX enzymes with selectivity for COX-2, and inhibiting phospholipase A2 activity to reduce the production of inflammatory leukotrienes.1,2,4

Diclofenac is an anti-inflammatory agent

Diclofenac is a potent anti-inflammatory agent1

Its effect on the COX-2 enzyme means that, unlike non-NSAID medications such as paracetamol, diclofenac not only provides pain relief but also treats inflammation – a root cause of pain.2,4

Diclofenac, an NSAID (and therefore in the same drug class as ketoprofen and ibuprofen), shows marked potency in its inhibition of the COX-2 enzyme.5

Diclofenac targets inflammation to strike pain at its source

Diclofenac-containing products

Voltaren Triple Effect 1.16% Emulgel

Voltaren Emulgel 1% gel

Self medication for the following indications: Local treatment of pain, inflammation and swelling due to:

  • Pain and inflammation and swelling in trauma of the tendons, ligaments, muscles and joints, e.g. due to sprains, strains and/or bruises and/or backache (e.g. sports injuries);
  • Localized forms of soft tissue rheumatism such as tendonitis (e.g. tennis elbow), bursitis. By Physicians order:
  • Pain caused by osteoarthritis of the peripheral joints, as of the knee or fingers.
Voltaren 12-hour 2.32% Emulgel

Voltaren Emulgel Forte 2%

Therapeutic indications Local treatment of pain, inflammation and swelling in adults and adolescents aged 12 years and over due to:

  • Soft tissue injuries: pain and inflammation and swelling in trauma of the tendons, ligaments, muscles and joints, e.g. due to sprains, strains and bruises and/or backache (e.g. sports injuries).
  • Localized forms of soft tissue rheumatism such as tendonitis (e.g. tennis elbow), bursitis.
  • By physician's order - pain caused by osteoarthrosis of the peripheral joints, as of the knee or fingers. The gel should not be used for more than 14 days.

Diclofenac – a potent anti-inflammatory ingredient1

Diclofenac-containing products

Diclofenac-containing products

Learn more about Voltaren products that contain this potent anti-inflammatory ingredient.1

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