Sensodyne Clinical Repair Toothpaste
Our next generation Sensodyne
Sensodyne Clinical Repair is clinically proven to relieve the pain of tooth sensitivity in 14 days and restores the lost layer of protection over sensitive areas of the tooth.
- Starts to restore sensitive teeth in 2 minutes*†
- Protects against the return of tooth sensitivity**
- 32% more effective cleaning action***
# 1 dentist recommendation for sensitive teeth++
*Starts to relieve tooth sensitivity in 14 days†The restoration was observed in laboratory tests.**With continuous use, brushing twice a day***Compared to Sensodyne Repair & Protect, in removing stains on the tooth surface++according to the geocartography survey 1.25
Patients with dentine hypersensitivity want an effective and long-lasting solution
Dentine hypersensitivity, or sensitive teeth, can have a big impact on patients’ oral health-related quality of life – affecting many aspects of day-to-day living.1-3
To achieve effective and long-lasting relief from dentine hypersensitivity,* target the root cause of the problem with comprehensive occlusion technology.4,5
Patients have the chance to target sensitive areas of the teeth, tackling the root cause of sensitivity, with Sensodyne Clinical Repair. With NovaMin: Innovative and effective occlusion technology.
*with continuous twice daily brushing
Evolving dentine hypersensitivity science, time and time again
Sensodyne has used its oral care expertise to adapt NovaMin technology for use in everyday oral care treatments. View the video as Darren Whitworth explains the nature of the unique technology and how Sensodyne scientists continue to improve our NovaMin formulations, to develop Sensodyne Clinical Repair.
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Starts to restore sensitive teeth in 2 minutes†*
![Image under a microscope of dentine tubules]()
Starts repairing from the first brush*+4
The top left SEM image shows a prepared dentine slab with open tubules – the block has been polished and acid etched to remove the smear layer.
The right-hand image shows dentine after one application of NovaMin for two minutes and subjected to an acid challenge. The majority of tubules are completely closed, and the remainder are at least partially closed.
*Starts to relieve tooth sensitivity in 14 days.†The restoration was observed in laboratory tests.Image from Greenspan DC. J Clin Dent 2010; 21:61-65
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Clinically proven to relieve sensitivity in 2 weeks5
![Graph to show reduction in Schiff sensitivity score in 2 weeks of sensitive teeth treatment with Sensodyne Clinical Repair Toothpaste]()
Clinically significant sensitivity improvements in 2 weeks5
The graph is taken from an exploratory, randomised, examiner blind, parallel group, 11-week controlled study in healthy adults with self-reported and clinically diagnosed dentine hypersensitivity (DH) with 135 subjects randomised to treatment.
The 3 treatment groups used either
- toothpaste with 5% Novamin + fluoride
- toothpaste with 8% arginine, calcium carbonate + fluoride
- a regular fluoride toothpaste.
Treatments were over-wrapped to maintain study blinding.
Two independent stimulus-based efficacy measures were used to assess DH: tactile (using a Yeaple probe) and evaporative (air) sensitivity (Schiff sensitivity score).
The 5% NovaMin toothpaste was shown to be effective in relieving DH and improvements continued throughout the 11-week study.
Graph adapted from Hall C et al. J Dent 2017; 60: 36-43
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Clinically proven to provide long-lasting sensitivity relief and ongoing protection*
![Graph to show reduction in Schiff sensitivity score after 24 weeks of sensitive teeth treatment with Sensodyne Clinical Repair Toothpaste]()
Effective protection against the pain of sensitive teeth, and enduring resilience
This data is from a 24 week, non-comparative clinical study in healthy adults (n=75) with clinically confirmed dentine hypersensitivity (DH). Subjects brushed for 24 weeks with a non-aqueous toothpaste with 5% NovaMin and 1426ppm fluoride.
DH was assessed at intervals over the 24-week period in response to evaporative (air) stimulus (Schiff sensitivity score) and a tactile stimulus.
All sensitivity measures demonstrated clinically significant ongoing reductions compared with baseline over the 24-week period.
This long-term data demonstrates ongoing efficacy over 6 months with twice daily brushing, associated with improved oral health-related quality of life.1,6
*with continuous twice daily brushingGraph adapted from Haleon Data on File Study RH01897 Synopsis Report 2014.
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Clinically proven improvements in oral health-related quality of life
![Graph to show improvement in oral health-related quality of life following treatment for dentine hypersensitivity]()
Long-term data demonstrated improved oral health-related quality of life with twice daily brushing6
This is from the same 24 week study. The dentine hypersensitivity experience questionnaire (DHEQ) was used to assess changes in subject-perceived DH before and during treatment in addition to traditional DH pain scores. These measures are indicative of oral health related quality of life (OHrQoL).
DHEQ measures demonstrated ongoing improvements in OHRQoL across the extended study period.
Graph adapted from Haleon Data on File Study RH01897 Synopsis Report 2014.
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More comprehensive occlusion than many other occluding toothpastes in vitro7
![Image of dentine tubules after treatment with toothpaste]()
Our NovaMin technology was significantly better than other occluding technologies tested in vitro7
This in vitro study used human and bovine dentine discs which were etched with 1% citric acid to remove the smear layer and then brushed with the tested toothpaste slurry for 2min and stored in artificial saliva for 12 hrs.
Scanning Electron Micrograph images were taken of the treated dentine samples.
Image adapted from Haleon Data on File, Report QD-RPT-112345, 2023 accepted for presentation at IADR New Orleans 2024.
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Forms a resilient reparative layer, harder than dentine8-11
![A graph to demonstrate the hardness of occlusive layers formed by Sensodyne Clinical Repair Toothpaste compared to dentine.]()
Provides a robust layer for sensitive teeth
In vitro studies have shown the hydroxyapatite-like layer formed with NovaMin is harder than dentine and highlight that the mechanical properties of the layers formed by desensitising agents are different.11
The graph is from a recent study showing the layer hardness on human dentine blocks following 4 days of twice-daily brushing for 30 seconds. Following each brush, samples were immersed in a 1:3 paste: artificial saliva (AS) slurry for 30 seconds. Layer hardness was measured by nano-indentation using a unique liquid cell set up to characterise the layers on a nanoscale level to avoid the substrate effect and to keep the dental tissue hydrated to provide a better mimic of in vivo conditions. A positive change from baseline is indicative of the surface becoming harder through the experiment.11
After four days of treatment Sensodyne Clinical Repair with NovaMin produced a significantly harder layer (p <0.05) compared to other occluding technologies. This layer was also 76% harder than the dentine control, which was statistically significant (p <0.05).11
Sensodyne Clinical Repair with NovaMin forms an occlusive layer, which is harder than natural dentine, over vulnerable areas of sensitive teeth for strong repair.
Image adapted from Haleon Data on File, Report QD-RPT-118201, 2024; accepted for presentation at IADR New Orleans 2024.
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Forms a reparative hydroxyapatite-like layer which is resistant to everyday oral challenges8-12
![Images of dentine treated with Sensodyne Clinical Repair Toothpaste before and after acid challenge to show resistance]()
Return resilience to sensitive teeth
In a recent in vitro study, human dentine block samples were brushed twice daily for 4 days, for 30 seconds each time, then immersed in a 1:3 Paste: artificial saliva slurry for an additional 30 seconds. SEM images were taken to confirm layer formation.11
After the hardness of the layers was measured (by nanoindentation as described previously) the dentine discs from all treatment groups were exposed to 1% citric acid (pH 3.8) for 2 minutes. The layer hardness was measured again, and samples were reimaged with SEM to evaluate the resistance of the occlusive layers that had formed by each toothpaste to an acid challenge.
We see in the SEM images dentine treated with artificial saliva and that treated with Clinical Repair. After 4 days of brushing with Clinical Repair, the tubules were occluded by the formation of a protective layer. After acid challenge the SEM shows that the layer formed by the NovaMin is still present.
Sensodyne Clinical Repair with NovaMin generates a protective mineral layer over exposed dentine to help protect from the pain of sensitive teeth. This reparative mineral layer is resistant to everyday oral challenges.
The same study also showed that Sensodyne Clinical Repair forms a reparative layer that is significantly more resistant to acid challenge than certain other occluding technologies.
Adapted from Haleon Data on File, Report QD-RPT-118201, 2024; accepted for presentation at IADR New Orleans 2024.
Recommend Sensodyne Clinical Repair Toothpaste to help patients tackle the root cause of tooth sensitivity
Sensodyne Clinical Repair Effective Clean Toothpaste
32% more effective cleaning action, Refreshing blend of peppermint and eucalyptus. Great tasting toothpaste with a rich foam.
*compared to Sensodyne Repair & Protection, in removing stains on the tooth surface
Sensodyne Clinical Repair Whitening Toothpaste
35% better whitening action.* Cool blend of peppermint and spearmint with a gentle whitening action. Great tasting toothpaste with a rich foam.
*compared to Sensodyne Repair & Protection, in removing stains on the tooth surface
#1 dentist recommended brand for people with sensitive teeth**
