Xylometazoline hydrochloride formulations
Otrivin offers several cold relief products specially formulated with xylometazoline hydrochloride
Nasal formulations containing xylometazoline provide rapid and effective relief of nasal congestion.1
Xylometazoline constricts dilated blood vessels in the nasal mucosa1,2
Xylometazoline is a sympathomimetic agent that binds to alpha adrenergic receptors causing vasoconstriction leading to decongestion of the nasal mucosa.1,2 This effect begins to take effect within 2 minutes of application and may remain active for up to 12 hours.1
A clinical study with xylometazoline demonstrated superiority to placebo at relieving nasal congestion3
Nasal sprays containing xylometazoline are proven to be significantly superior to placebo at relieving nasal congestion with decongestion effects shown for up to 12 hours.1,3 Xylometazoline was also found to significantly improve individual common cold symptoms, such as easier breathing, leading to significantly greater patient satisfaction with treatment.3 The activity of xylometazoline occurs as quickly as within 2 minutes.1
Xylometazoline provides rapid and long-lasting relief of nasal congestion1
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Xylometazoline acts locally to constrict dilated blood vessels of the nasal mucosa1,2
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Strong vasoconstriction of dilated blood vessels in the nasal mucosa1,2
Vasoconstriction subsequently results in decongestion of the nasal mucosa and neighbouring tissues of the pharynx, improving nasal airflow.1,2
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Benefits of topical decongestants
Topical decongestants in the form of nasal sprays, provide several advantages over oral decongestants:
- They act locally on the nasal mucosa as opposed to requiring absorption and transportation through the bloodstream.
- Relief is immediate within a matter of minutes.2
- They provide a longer duration of action.2
- They have minimal systemic absorption and subsequently fewer systemic side effects.4
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Xylometazoline offers fast-acting and long-lasting relief1
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Xylometazoline hydrochloride begins to take effect within 2 minutes of application and may remain active for up to 12 hours.1 This is in contrast to oral decongestants, which may take up to half an hour to come into effect and last for only up to 6 hours.2
Discover the Otrivin range with xylometazoline hydrochloride
Otrivin Adult Nasal Drops
Otrivin Adult Nasal Drops unblocks the nose within minutes and lasts for up to 12 hours.
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Otrivin Children Nasal Drops
Otrivin Children Nasal Drops rapidly unblocks the nose in children between 1 and 11 years old with xylometazoline.
Otrivin – your Nasal HealthPartner
